You could squirt WD40 in there all day and not hurt anything, that'll probably do it. If you can't turn it, you could remove the whole piece from the block to work on it. Be very careful not to snap it off in the block, that would require some work with an easy-out. You could replace the whole assembly with a plug, it's probably metric so measure the threads before you try to jam something in there. I'm sure you could get a new one from Toyota.
I think some penetrating oil will loosen that thing right up.
The lower oil cooler hose having water in it shouldn't have hurt anything. Just check for leaks when you get it back in the water